منابع مشابه
Drug-Related Genomics in Cancer and Immunological Diseases
Drug-related genes are defined as the genes which encode enzymes, transporters, and targets related to drug absorption, distribution, and metabolism to excretion. The studies on drug-related genomics in cancer and immunological diseases could enhance the understanding of the role of drug-related genes in the occurrence and development of cancer or immunological diseases. Pharmacogenomics resear...
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Processed antigen reacts selectively with lymphocytes bearing .appropriate surface immunoglobulin molecules resulting in the clonal proliferation of these cells, producing circulating immunoglobulin (humoral immunity) or non-circulating immunoglobulins (cellular immunity). High levels of circulating immunoglobulins (lgM & lgG) occur in protozoa and helminths infections. Reaginic antibodies a...
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The proportion of elderly people rises in the developed countries. The increased susceptibility of the elderly to infectious diseases is caused by immune dysfunction, especially T cell functional decline. Age-related hematopoietic stem cells deviate from lymphoid lineage to myeloid lineage. Thymus shrinks early in life, which is followed by the decline of naïve T cells. T-cell receptor repertoi...
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Clinical neurology has been traditionally considered as an academic speciality in which the specialist regurgitates his/her knowledge of neurology without being able to do much for the patient. This attitude is no longer acceptable. Surge of information and discoveries in neurosciences within the last two decades translated into therapeutic interventions which is literally life saving in some o...
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The innate and the adaptive immune systems work in concert to deal with pathologies introduced by internal and external factors (e.g., viruses, bacteria, and fungi) – some of which may be associated with the development of autoimmune and cancerous cells. Mechanistically, there are internal factors that are responsible for the hypo-and hyperfunction of immune tolerance apparatus. Consequently, i...
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ژورنال
عنوان ژورنال: International Journal of Genomics
سال: 2014
ISSN: 2314-436X,2314-4378
DOI: 10.1155/2014/306980